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LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: from discovery to clinical proof of concept

PMID: 14 ZatorskiHSalagaMFichnaJ

In diabetics, the release of insulin is a powerful benefit that helps regulate blood sugar

Conversely to the hormone leptin, ghrelin stimulates neuropeptide Y neurons and inhibits hypothalamic POMC neurons [89]